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hallmarks of cancer in a sentence

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  • Hyperplasia ( uncontrolled cell growth ) is one of the hallmarks of cancer.
  • Such fast growth is a hallmark of cancer.
  • An important hallmark of cancer, Akt is part of the cell survival pathways by inhibiting apoptosis.
  • In some cancers, this receptor is altered to cause uncontrolled cell division, a hallmark of cancer.
  • Therefore, the alteration of cellular and energy metabolism has been suggested as one of The Hallmarks of Cancer.
  • This contributes to many of the hallmarks of cancer including proliferative signaling, growth activation, and replicative immortality.
  • The hallmarks of cancer and possible mechanisms of radiation damage that lead to these changes observed in all human tumors.
  • Extreme weight loss, known as wasting, long recognized and dreaded as a hallmark of cancer, has puzzled researchers for decades.
  • A chemical may act as a co-carcinogen even if it does not cause direct DNA damage such as hallmark of cancer.
  • With developments in our understanding of the hallmarks of cancer, however, novel approaches to specifically targeting and treating FDCS are being developed.
  • It's difficult to see hallmarks of cancer in a sentence .
  • The expansion of a particular clone of immune B cells is usually interpreted by clinicians as evidence of unrestricted cell growth, the hallmark of cancer.
  • Since aberrant gene expression is a hallmark of cancer, modulating these endogenous genes'expression levels could potentially act as a therapy for multiple cancer types.
  • The drug, clotrimazole, can drastically curb uncontrolled cell growth _ a hallmark of cancer and certain other diseases, the scientists report in the journal Nature Medicine.
  • Macroscopic tumors are now beginning to be described in terms of their underlying genetic changes, providing additional data to refine the framework described in The Hallmarks of Cancer.
  • When these genes get damaged by mutations, they become like switches stuck in the on position, and the cell starts to divide uncontrollably, the hallmark of cancer.
  • Interestingly, high levels of glycolysis and the production of lactate, as shown in hypoxic tumor cells, is hallmark of cancer cells even in the presence of oxygen.
  • In this case, the co-receptor is functioning in a critical regulatory manner to reduce signals that instruct the cell to grow and migrate  the hallmarks of cancer.
  • Tyrosine kinases can contain mutations that cause them to become constitutively active, or stuck in the  on position, resulting in unregulated cell division ( a hallmark of cancer ).
  • This overexpression triggers a promotion of  anti-apoptotic activity of Akt in prostate cancer, meaning that these cells have gained the ability to avoid the normal cell death pathways ( a common hallmark of cancer ).
  • ""'The Hallmarks of Cancer "'" is a seminal peer-reviewed article published in the journal " Cell " in January 2000 by the cancer researchers Douglas Hanahan and Robert Weinberg.
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